Background: Acute tubulointerstitial nephritis (ATIN) is a very rare paraneoplastic manifestation in patients with multiple myeloma (MM).It is an uncommon pattern of renal disease in such patients.Case presentation: We report a case of an 82-year-old male who was admitted with 3701129802670 acute kidney injury.Renal biopsy showed typical findings o
A Rare Cause of Hemoperitoneum in a Patient with Cirrhosis and Portal Hypertension
A 48-year-old man, diagnosed case of portal hypertension secondary to alcohol related cirrhosis of the liver, presented to the gastrointestinal (GI) Bleed Unit, with jaundice and worsening abdominal distension for a period of five days.Clinical examination revealed an emaciated patient in grade 2 hepatic encephalopathy with pulse rate 98 per minute
Autoregulation of JARID2 through PRC2 interaction with its antisense ncRNA
Abstract Objective JARID2 is a member of chromatin-modifying Polycomb Repressive Complex-2 or PRC2.It plays a role in motiv thrill pink yellow recruiting PRC2 to developmental genes and regulating its activity.JARID2 along with PRC2 is indispensable for normal development.However, it remains unclear how JARID2 expression itself is regulated.Recentl